Dr. Kerstin Johann

Dr. Kerstin Johann


Kerstin Johann studied Biomedical Chemistry at the Johannes Gutenberg University Mainz and graduated in 2016 (M.Sc.). During her master thesis she synthesized polypept(o)ide-based carrier systems for the application in cancer immunotherapy. Her current PhD research is focused on the preparation of carrier systems for the delivery of anti-tuberculosis drugs and the synthesis of brush polymers for in vivo click chemistry.



Institut für Organische Chemie
Johannes Gutenberg-Universität Mainz
Duesbergweg 10-14
55128 Mainz  

+49 6131 39 25468

Research topic

Functional Polypept(o)ides for Imaging and Therapy


Tetrazine- and trans-cyclooctene-functionalised polypept(o)ides for fast bioorthogonal tetrazine ligation

Kerstin Johann, Dennis Svatunek, Christine Seidl, Silvia Rizzelli, Tobias A. Bauer, Lydia Braun, Kaloian Koynov, Hannes Mikula and Matthias Barz

Polym. Chem., 2020, Advanced Article

DOI: https://doi.org/10.1039/D0PY00375A

Trans-Cyclooctene-Functionalized PeptoBrushes with Improved Reaction Kinetics of the Tetrazine Ligation for Pretargeted Nuclear Imaging

E. Johanna L. Stéen, Jesper T. Jørgensen, Kerstin Johann, Kamilla Nørregaard, Barbara Sohr, Dennis Svatunek, Alexander Birke, Vladimir Shalgunov, Patricia E. Edem, Raffaella Rossin, Christine Seidl, Friederike Schmid, Marc S. Robillard, Jesper L. Kristensen, Hannes Mikula, Matthias Barz, Andreas Kjær, Matthias M. Herth

ACS Nano 2020, 14, 1, 568-584

DOI: https://doi.org/10.1021/acsnano.9b06905

Investigation of α-amino acid N-carboxyanhydrides by X-ray diffraction for controlled ring-opening polymerization

Olga Schäfer, Dieter Schollmeyer, Alexander Birke, Regina Holm, Kerstin Johann, Christian Muhl, Christine Seidl, Benjamin Weber, Matthias Barz

Tetrahedron Letters 201960, 272–275, DOI: doi.org/10.1016/j.tetlet.2018.12.028

Enhanced Permeability and Retention-like Extravasation of Nanoparticles from the Vasculature into Tuberculosis Granulomas in Zebrafish and Mouse Models

Federico FenaroliUrska RepnikYitian XuKerstin JohannSimon Van HerckPradip DeyFrode Miltzov SkjeldalDominik M. FreiShahla BagherifamAgnese KocereRainer HaagBruno G. De GeestMatthias BarzDavid G. Russell, and Gareth Griffiths

ACS Nano201812 (8), pp 8646–8661. DOI: 10.1021/acsnano.8b04433

Two-photon absorption dye based on 2,5-bis(phenylacrylonitrile)thiophene with aggregration enhanced fluorescence

Tobias Johann, Kerstin Schmidt, Prem Prabhakaran, Rudolf Zentel, and Kwang-Sup Lee

Optical Materials Express Vol. 6, Issue 4, pp. 1296-1305, (2016) DOI: 10.1364/OME.6.001296