Dr. Philipp Heller
research topic
Peptoplexes as Artificial Viruses for Nucleic Acid Vaccine Delivery
publications
Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines
Philipp Heller, Dominika Hobernik, Ulrich Lächelt, Meike Schinnerer, Benjamin Weber, Manfred Schmidt, Ernst Wagner, Matthias Bros, Matthias Barz
Journal of Controlled Release 2017, 258, 146–160. DOI: 10.1016/j.jconrel.2017.05.012
Influence of Block Ionomer Microstructure on Polyplex Properties: Can Simulations Help to Understand Differences in Transfection Efficiency?
Philipp Heller, Jiajia Zhou, Benjamin Weber, Dominika Hobernik, Matthias Bros, Friederike Schmid, Matthias Barz
Small 2017, 13, 1603694. DOI: 10.1002/smll.201603694
Synthesis and Characterization of Stimuli-Responsive Star-Like Polypept(o)ides: Introducing Biodegradable PeptoStars
Regina Holm, Benjamin Weber, Philipp Heller, Kristina Klinker, Dana Westmeier, Dominic Docter, Roland H. Stauber, Matthias Barz
Macromol. Biosci. 2017, 17, 1600514. DOI: 10.1002/mabi.201600514
Evaluating chemical ligation techniques for the synthesis of block copolypeptides, polypeptoids and block copolypept(o)ides: a comparative study
Kristina Klinker, Regina Holm, Philipp Heller, Matthias Barz
Polym. Chem. 2015, 6, 4612–4623. DOI: 10.1039/c5py00461f
Directed Interactions of Block Copolypept(o)ides with Mannose-Binding Receptors:PeptoMicelles Targeted to Cells of the InnateImmune System
Philipp Heller, Nicole Mohr, Alexander Birke, Benjamin Weber, Angelika Reske-Kunz, Matthias Bros, Matthias Barz
Macromol. Biosci. 2015, 15, 63–73. DOI: 10.1002/mabi.201400417
Synthesis and Sequential Deprotection of Triblock Copoly-pept(o)ides Using Orthogonal Protective Group Chemistry
Philipp Heller, Benjamin Weber, Alexander Birke, Matthias Barz
Macromol. Rapid Commun. 2015, 36, 38−44.
Introducing PeptoPlexes: Polylysine-block-Polysarcosine Based Polyplexes for Transfection of HEK 293T Cells
Philipp Heller, Alexander Birke, David Huesmann, Benjamin Weber, Karl Fischer, Angelika Reske-Kunz, Matthias Bros, Matthias Barz
Macromol. Biosci. 2014, 14, 1380–1395. DOI: 10.1002/mabi.201400167