David Schwiertz

David Schwiertz


David Schwiertz studied Biomedical Chemistry at the Johannes Gutenberg University Mainz and graduated in 2018 (M.Sc.). His current PhD research is focused on the synthesis of polypept(o)idic heteroarm star copolymers with precisely controlled structures for crosslinkable micelles as drug delivery systems.



Institut für Organische Chemie
Johannes Gutenberg-Universität Mainz
Duesbergweg 10-14
55128 Mainz

+49 6131 39 25467

Research Topic

Synthesis and Characterization of Miktoarm Star Copolymers as potential Nano Drug Delivery Systems


Influence of Riboflavin Targeting on Tumor Accumulation and Internalization of Peptostar Based Drug Delivery Systems

Milita Darguzyte, Regina Holm, Jasmin Baier, Natascha Drude, Jennifer Schultze, Kaloian Koynov, David Schwiertz, Seyed Mohammadali Dadfar, Twan Lammers, Matthias Barz, Fabian Kiessling

Bioconjugate Chem., 2020, 31, 12, 2691-2696

DOI: https://doi.org/10.1021/acs.bioconjchem.0c00593

Facile synthesis of amphiphilic AB3 and A3B miktoarm PeptoMiktoStars

David Schwiertz, Regina Holm, Matthias Barz

Polymer Journal, 52, 119-132 (2020)

DOI: https://doi.org/10.1038/s41428-019-0269-1

Multifunctional Cationic PeptoStars as siRNA Carrier: Influence of Architecture and Histidine Modification on Knockdown Potential

Regina Holm, David Schwiertz, Benjamin Weber, Jennifer Schultze, Jasmin Kuhn, Kaloian Koynov, Ulrich Lächelt, Matthias Barz

Macromolecular Bioscience, 2019, 1900152

DOI: //doi.org/10.1002/mabi.201900152

Polysarcosine-Based Lipids: From Lipopolypeptoid Micelles to Stealth-Like Lipids in Langmuir Blodgett Monolayers

Benjamin Weber, Christine Seidl, David Schwiertz, Martin Scherer, Stefan Bleher, Regine Süss, Matthias Barz

Polymers 20168, 427-440. DOI: 10.3390/polym8120427