Meike Schinnerer studied Chemistry at the Johannes Gutenberg University Mainz and obtained her graduate degree in 2014. Her PhD research focuses on the synthesis of cylindrical polypept(o)ide brushes with defined morphologies, focusing on the precise characterization of the nanoparticles (e.g. DLS, SLS, FCS, AFM). As part of the SFB1066, she synthesizes brush-conjugates with bioactive components for application in tumor immunotherapy. Further, Meike investigates the aggregation behavior of nanoparticles in human serum using dynamic light scattering.

mschin@uni-mainz.de

Institut für Organische Chemie
Johannes Gutenberg-Universität Mainz
Duesbergweg 10-14
55128 Mainz  

+49 6131 39 23388

Polypept(o)ide Brushes as Multifunctional Vaccines for Application in Tumor Immunotherapy

Density of Conjugated Antibody Determines the Extent of Fc Receptor Dependent Capture of Nanoparticles by Liver Sinusoidal Endothelial Cells

Cinja Kappel, Christine Seidl, Carolina Medina-Monatano, Meike Schinnerer, Irina Alberg, Christian Leps, Julian Sohl, Ann-Kathrin Hartmann, Michael Fichter, Michael Kuske, Jenny Schunke, Gabor Kuhn, Ingrid Tubbe, David Paßlick, Dominika Hobernik, Rebekka Bent, Katharina Haas, Evelyn Montermann, Kerstin Walzer, Mustafa Diken, Manfred Schmidt, Rudolf Zentel, Lutz Nuhn, Hansjörg Schild, Stefan Tenzer, Volker Mailänder, Matthias Barz, Matthias Bros, Stephan Grabbe

ACS Nano, 2021, 15, 9, 15191-15209

DOI: https://doi.org/10.1021/acsnano.1c05713

Monitoring drug nanocarriers in human blood by near-infrared fluorescence correlation spectroscopy

Inka Negwer, Andreas Best, Meike Schinnerer, Olga Schäfer, Leon Capeloa, Manfred Wagner, Manfred Schmidt, Volker Mailänder, Mark Helm, Matthias Barz, Hans-Jürgen Butt & Kaloian Koynov 

Nature Communications, 9, 5306 (2018) DOI: doi.org/10.1038/s41467-018-07755-0

Site-Specific DBCO Modification of DEC205 Antibody for Polymer Conjugation

Simone Beck, Jennifer Schultze, Hans-Joachim Räder, Regina Holm, Meike Schinnerer, Matthias Barz, Kaloian Koynov and Rudolf Zentel

Polymers 2018, 10(2), 141; doi:10.3390/polym10020141

Folding induced supramolecular assembly into pH-responsive nanorods with a protein repellent shell

Ronja Otter,  Kristina Klinker,  Daniel Spitzer,  Meike Schinnerer,  Matthias Barz and  Pol Besenius

Chem. Commun., 2018, 54, 401-404 . DOI: 10.1039/c7cc08127h

Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines

Philipp Heller, Dominika Hobernik, Ulrich Lächelt, Meike Schinnerer, Benjamin Weber, Manfred Schmidt, Ernst Wagner, Matthias Bros, Matthias Barz

Journal of Controlled Release 2017, 258, 146–160. DOI: 10.1016/j.jconrel.2017.05.012

Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size,Shape,and Function of Core Cross-Linked Nanostructures

Kristina Klinker ,Olga Schäfer, David Huesmann, Tobias Bauer, Leon Capelôa, Lydia Braun, Natascha Stergiou, Meike Schinnerer, Anjaneyulu Dirisala, Kanjiro Miyata, Kensuke Osada, Horacio Cabral, Kazunori Kataoka, Matthias Barz

Angew. Chem. Int. Ed. 2017, 56, 9608–9613.

DOI: 10.1002/anie.201702624

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha

Kienzle,* S. Kurch, J. Schlöder, C. Berges, R. Ose, J. Schupp, A. Tuettenberg, H. Weiss, J. Schultze, S. Winzen, M. Schinnerer, K. Koynov, M. Mezger, N. K. Haass, W. Tremel Adv. Healthcare Mater. 2017, 6, 1700012.