Our Skills
Amino Acids Synthesis
Development of protective groups for amino acids to enable the straight-forward synthesis of reactive polypeptides, e.g. combining stability in peptide synthesis with chemoselective reactivity in postpolymerization modification techniques.
Polymer Synthesis and Characterization
Development and detailed physicochemical analysis of various polymer architectures, e.g. (multi)block copolymers, brush polymers with homo or block copolymer side chains, star-like polymers or lipopolymers, which combine the polypeptoids polysarcosine with different polypeptide segments.
Synthesis of Functional Nanoparticles
Development of robust, scalable synthetic methods to derive functional nanoparticles with compartmentalized functionalities and precise control over size and shape to tailor particle properties to specific needs in individual applications.
Biomedical Applications
Understanding the interactions of nanoparticles with living organism to develop nanoparticle based tools for diagnosis and therapy of cancer, acute or chronic inflammations, bacterial infections or neurodegenerative diseases.
Latest News
Congratulations
Congratulation Dr. Tobias Bauer and Dr. Liya Heidary Fard for succsessfully defending their PhD theses!! Best wishes for you!
Welcome
We are welcoming Bonan Zhao as our new PhD student in our group!
Congratulations
We congratulate Jeffrey van der Sluis for successfully finishing his Master’s thesis!
Our latest publicatons
Folding induced supramolecular assembly into pH-responsive nanorods with a protein repellent shell
Polysarcosine-containing copolymers: Synthesis, characterization, self-assembly, and applications
Combining Orthogonal Reactive Groups in Block Copolymers for Functional Nanoparticle Synthesis in a Single Step
Immunomodulatory Therapy of Inflammatory Liver Disease Using Selectin-Binding Glycopolymers
Combining reactive triblock copolymers with functional cross-linkers: A versatile pathway to disulfide stabilized-polyplex libraries and their application as pDNA vaccines
Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size,Shape,and Function of Core Cross-Linked Nanostructures
Balancing Passive and Active Targeting to Different Tumor Compartments Using Riboflavin-Functionalized Polymeric Nanocarriers
Orthogonally reactive amino acids and end groups in NCA polymerization
Polypept(o)ides: Hybrid Systems Based on Polypeptides and Polypeptoids
Solution Properties of Polysarcosine: From Absolute and Relative Molar Mass Determinations to Complement Activation