Leon Capeôla

Leon Capeôla

About

Leon Capelôa pursues his master degree concluding his studies in biomedical chemistry at the JGU Mainz. His current work is focused on the analysis of the self-assembly process of block copolypept(o)ides and the potential to control this process by secondary structure formation and their suppression. Further, his research covers the synthesis and evaluation of these materials as delivery systems for therapeutic agents such as siRNA.

Contact

Institut für Organische Chemie
Johannes Gutenberg-Universität Mainz
Duesbergweg 10-14
55128 Mainz  

+49 6131 39 25468

Research topic

Polymer Architectures by Directed Self-Assembly for siRNA Delivery

Publications

Secondary-Structure-Driven Self-Assembly of Reactive Polypept(o)ides: Controlling Size,Shape,and Function of Core Cross-Linked Nanostructures

Kristina Klinker ,Olga Schäfer, David Huesmann, Tobias Bauer, Leon Capelôa, Lydia Braun, Natascha Stergiou, Meike Schinnerer, Anjaneyulu Dirisala, Kanjiro Miyata, Kensuke Osada, Horacio Cabral, Kazunori Kataoka, Matthias Barz

Angew. Chem. Int. Ed. 201756, 9608–9613.

DOI: 10.1002/anie.201702624

Sekundärstrukturbildung als Triebkraft für die Selbstorganisation reaktiver Polypept(o)ide: Steuerung von Größe, Form und Funktion kernvernetzter Nanostrukturen

Kristina Klinker, Olga Schäfer, David Huesmann, Tobias Bauer, Leon Capelôa, Lydia Braun, Natascha Stergiou, Meike Schinnerer, Anjaneyulu Dirisala, Kanjiro Miyata, Kensuke Osada, Horacio Cabral, Kazunori Kataoka, Matthias Barz

Angew. Chem. 2017 , 129, 9737–9742. DOI: 10.1002/ange.201702624